Dr Helena Azevedo

Helena Azevedo

Reader in Biomedical Engineering & Biomaterials
Biomacromolecular and Biomaterials Design Lead

School of Engineering and Materials Science
Queen Mary University of London
+44 (0)20 7882 5502

www.sems.qmul.ac.uk/h.azevedo
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Publications

Publications of specific relevance to

2022

Azevedo HS and Mata A (2022). Embracing complexity in biomaterials design. Eslevier  Biomaterials and Biosystems  vol. 6, 100039-100039. 10.1016/j.bbiosy.2022.100039
Redondo-Gómez C, Padilla-Lopátegui S, Mata A and Azevedo HS (2022). Peptide Amphiphile Hydrogels Based on Homoternary Cucurbit[8]uril Host-Guest Complexes. Bioconjugate Chemistry  vol. 33, (1) 111-120. 10.1021/acs.bioconjchem.1c00441

2021

Teng C, Li B, Lin C, Xing X, Huang F, Yang Y, Li Y, Azevedo HS and He W (2021). Targeted delivery of baicalein-p53 complex to smooth muscle cells reverses pulmonary hypertension. Elsevier  Journal of Controlled Release  vol. 341, 591-604. 10.1016/j.jconrel.2021.12.006
Mendoza-martinez AK, Loessner D, Mata A and Azevedo HS (2021). Modeling the tumor microenvironment of ovarian cancer: The application of self-assembling biomaterials. Cancers  vol. 13, (22) 10.3390/cancers13225745
Li Y, Teng C, Azevedo HS, Yin L and He W (2021). Cocrystallization-like strategy for the codelivery of hydrophobic and hydrophilic drugs in a single carrier material formulation. Chinese Chemical Letters  vol. 32, (10) 3071-3075. 10.1016/j.cclet.2021.03.085
Shi Y, Wareham DW, Yuan Y, Deng X, Mata A and Azevedo HS (2021). Polymyxin B-Triggered Assembly of Peptide Hydrogels for Localized and Sustained Release of Combined Antimicrobial Therapy. Advanced Healthcare Materials  10.1002/adhm.202101465
Pang X, Li W, Chang L, Gautrot JE, Wang W and Azevedo HS (2021). Hyaluronan (HA) Immobilized on Surfaces via Self-Assembled Monolayers of HA-Binding Peptide Modulates Endothelial Cell Spreading and Migration through Focal Adhesion. American Chemical Society  Acs Applied Materials and Interfaces  vol. 13, (22) 25792-25804. 10.1021/acsami.1c05574
Ismail AS, Goodwin GR, Castrejon-Pita JR, Noyce AJ and Azevedo HS (2021). A novel capsule-based smell test fabricated via coaxial dripping. The Royal Society  Journal of The Royal Society Interface  vol. 18, (177) 10.1098/rsif.2021.0039
Li Y, Teng C, Azevedo HS, Yin L and He W (2021). Cocrystallization-like strategy for the codelivery of hydrophobic and hydrophilic drugs in a single carrier material formulation. Elsevier  Chinese Chemical Letters  vol. 32, (10) 3071-3075. 10.1016/j.cclet.2021.03.085
Lyu Y and Azevedo HS (2021). Supramolecular Hydrogels for Protein Delivery in Tissue Engineering. Mdpi Ag  Molecules  vol. 26, (4) 10.3390/molecules26040873
Collis DWP, Yilmaz G, Yuan Y, Monaco A, Ochbaum G, Shi Y, O’Malley C, Uzunova V, Napier R, Bitton R, Becer CR and Azevedo HS (2021). Hyaluronan (HA)-inspired glycopolymers as molecular tools for studying HA functions. Royal Society of Chemistry  Rsc Chemical Biology  10.1039/d0cb00223b
Shi Y, Wareham DW, Phee LM and Azevedo HS (2021). CHAPTER 12: Self-assembled Peptide Nanostructures for Antibacterial Applications. Rsc Soft Matter  10.1039/9781839161148-00395
Azevedo HS, Mano JF and Borges J (2021). Preface. 10.1039/9781839161124-00750

2020

Shi Y, Summers PA, Kuimova MK and Azevedo HS (2020). Unravelling the enzymatic degradation mechanism of supramolecular peptide nanofibers and its correlation with their internal viscosity. American Chemical Society (Acs)  Nano Letters  10.1021/acs.nanolett.0c02781
Wu L, Di Cio S, Azevedo HS and Gautrot JE (2020). Photoconfigurable, Cell-Remodelable Disulfide Cross-linked Hyaluronic Acid Hydrogels. American Chemical Society  Biomacromolecules  10.1021/acs.biomac.0c00603
Bekmurzayeva A, Dukenbayev K, Azevedo HS, Marsili E, Tosi D and Kanayeva D (2020). Optimizing Silanization to Functionalize Stainless Steel Wire: Towards Breast Cancer Stem Cell Isolation. Mdpi  Materials (Basel)  vol. 13, (17) 10.3390/ma13173693
Azevedo HS, Perry SL, Korevaar PA and Das D (2020). Complexity emerges from chemistry. Nat Chem  10.1038/s41557-020-0537-x
Redondo-Gómez C, Padilla Lopategui S, Azevedo HS and Mata A (2020). Host-guest-mediated epitope presentation on self-assembled peptide amphiphile hydrogels. American Chemical Society  Acs Biomaterials Science and Engineering  10.1021/acsbiomaterials.0c00549
Teng C, Lin C, Huang F, Xing X, Chen S, Ye L, Azevedo HS, Xu C, Wu Z, Chen Z and He W (2020). Intracellular codelivery of anti-inflammatory drug and anti-miR155 to treat inflammatory disease. Elsevier  Acta Pharmaceutica Sinica B  10.1016/j.apsb.2020.06.005
Maslova E, Shi Y, Sjöberg F, Azevedo HS, Wareham DW and McCarthy RR (2020). An Invertebrate Burn Wound Model That Recapitulates the Hallmarks of Burn Trauma and Infection Seen in Mammalian Models. Frontiers Media Sa  Frontiers in Microbiology  vol. 11, 10.3389/fmicb.2020.00998
Radvar E, Shi Y, Grasso S, Edwards-Gayle CJC, Liu X, Mauter MS, Castelletto V, Hamley IW, Reece MJ and Azevedo HS (2020). Magnetic field-induced alignment of nanofibrous supramolecular membranes: a molecular design approach to create tissue-like biomaterials. American Chemical Society  Acs Applied Materials and Interfaces  10.1021/acsami.0c05191
Wu Y, Wang W, Mata A, Pugno N, Azevedo H, Karabasov S and Titirici M-M (2020). Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices. Nature Research (Part of Springer Nature)  Nature Communications  10.1038/s41467-020-14716-z
Topping LM, Thomas BL, Rhys HI, Tremoleda JL, Foster M, Seed M, Voisin MB, Vinci C, Law HL, Perretti M, Norling LV, Azevedo HS and Nissim A (2020). Targeting Extracellular Vesicles to the Arthritic Joint Using a Damaged Cartilage-Specific Antibody. Frontiers Media  Frontiers in Immunology  vol. 11, 10.3389/fimmu.2020.00010

2019

Shahane G, Ding W, Palaiokostas M, Azevedo HS and Orsi M (2019). Interaction of Antimicrobial Lipopeptides with Bacterial Lipid Bilayers. Journal of Membrane Biology  vol. 252, (4-5) 317-329. 10.1007/s00232-019-00068-3
Xin X, Du X, Xiao Q, Azevedo HS, He W and Yin L (2019). Drug Nanorod-Mediated Intracellular Delivery of microRNA-101 for Self-sensitization via Autophagy Inhibition. Springer Science and Business Media Llc  Nano-Micro Letters  vol. 11, (1) 10.1007/s40820-019-0310-0
Shi Y, Ferreira D, Banerjee J, Pickford A and Azevedo HS (2019). Tuning the Matrix Metalloproteinase-1 Degradability of Peptide Amphiphile Nanofibers through Supramolecular Engineering. Royal Society of Chemistry (Rsc)  Biomaterials Science  10.1039/c9bm00949c
Pang X, O'Malley C, Borges J, Rahman MM, Collis DWP, Mano JF, Mackenzie IC and S. Azevedo H (2019). Supramolecular Presentation of Hyaluronan onto Model Surfaces for Studying the Behaviour of Cancer Stem Cells. Wiley  Advanced Biosystems  1900017-1900017. 10.1002/adbi.201900017
Pang X, Li W, Landwehr E, Yuan Y, Wang W and Azevedo HS (2019). Mimicking the endothelial glycocalyx through the supramolecular presentation of hyaluronan on patterned surfaces. Faraday Discuss  10.1039/c9fd00015a
Radvar E and Azevedo HS (2019). Supramolecular Nanofibrous Peptide/Polymer Hydrogels for the Multiplexing of Bioactive Signals. American Chemical Society (Acs)  Acs Biomaterials Science & Engineering  10.1021/acsbiomaterials.9b00941
Lombardi L, Shi Y, Falanga A, Galdiero E, de Alteriis E, Franci G, Chourpa I, Azevedo HS and Galdiero S (2019). Enhancing the Potency of Antimicrobial Peptides through Molecular Engineering and Self-Assembly. Biomacromolecules  vol. 20, (3) 1362-1374. 10.1021/acs.biomac.8b01740
Li B, He W, Ye L, Zhu Y, Tian Y, Chen L, Yang J, Miao M, Shi Y, Azevedo HS, Ma Z and Hao K (2019). Targeted Delivery of Sildenafil for Inhibiting Pulmonary Vascular Remodeling. Hypertension  vol. 73, (3) 703-711. 10.1161/HYPERTENSIONAHA.118.11932
Azevedo HS, Braunschweig AB, Chiechi RC, Diaz Fernandez Y, Gildersleeve JC, Godula K, Hartmann L, Miura Y, Schmidt S, Turnbull WB and Zhou D (2019). Glycan interactions on glycocalyx mimetic surfaces: General discussion. Faraday Discussions  vol. 219, 183-188. 10.1039/C9FD90063B
Azevedo HS, Braunschweig A, Byrne JP, Diaz Fernandez Y, Gildersleeve J, Hartmann L, Huang M, Nelson A, Ravoo BJ, Schmidt S, Tammelin T, Turnbull WB, Zheng Z and Zhou D (2019). Multidimensional micro- and nano-printing technologies: General discussion. Faraday Discussions  vol. 219, 73-76. 10.1039/C9FD90061F
Azevedo HS, Braunschweig AB, Chiechi RC, Claridge SA, Cronin L, Diaz Fernandez Y, Feizi T, Hartmann L, Huang M, Miura Y, Palma M, Qiu X, Ravoo BJ, Schmidt S, Turnbull WB, Werner C, Zheng Z and Zhou D (2019). New directions in surface functionalization and characterization: General discussion. Faraday Discussions  vol. 219, 252-261. 10.1039/C9FD90064K
Azevedo HS (2019). Biomaterials inspired by biology: From molecules to self-assembly. Encyclopedia of Tissue Engineering and Regenerative Medicine  10.1016/B978-0-12-801238-3.11133-X

2018

Bekmurzayeva A, Duncanson WJ, Azevedo HS and Kanayeva D (2018). Surface modification of stainless steel for biomedical applications: Revisiting a century-old material. Materials Science and Engineering C  10.1016/j.msec.2018.08.049
Radvar E and Azevedo HS (2018). Supramolecular Peptide/Polymer Hybrid Hydrogels for Biomedical Applications. Macromol Biosci  e1800221-e1800221. 10.1002/mabi.201800221
Banerjee J and Azevedo HS (2018). Correction to 'Crafting of functional biomaterials by directed molecular self-assembly of triple helical peptide building blocks'. Interface Focus  vol. 8, (4) 10.1098/rsfs.2018.0017
Shi Y, Lin R, Cui H and Azevedo HS (2018). Multifunctional Self-Assembling Peptide-Based Nanostructures for Targeted Intracellular Delivery: Design, Physicochemical Characterization, and Biological Assessment. Methods Mol Biol  vol. 1758, 11-26. 10.1007/978-1-4939-7741-3_2
Mata A, Azevedo HS, Connelly J and Gautrot J (2018). Bioengineering Complexity and Tuneability in Hydrogels. Hydrogels  Taylor & Francis  10.1201/9781315152226-17
Chen Q, Passos A, Balabani S, Chivu A, Zhao S, Azevedo HS, Butler P and Song W (2018). Semi-interpenetrating network hyaluronic acid microgel delivery systems in micro-flow. J Colloid Interface Sci  vol. 519, 174-185. 10.1016/j.jcis.2018.02.049
Banerjee J, Radvar E and Azevedo HS (2018). Self-assembling peptides and their application in tissue engineering and regenerative medicine. Peptides and Proteins as Biomaterials For Tissue Regeneration and Repair  10.1016/B978-0-08-100803-4.00010-3
Shuturminska K, O’Malley C, Collis DWP, Conde J and Azevedo HS (2018). Displaying biofunctionality on materials through templated self-assembly. Self-Assembling Biomaterials: Molecular Design, Characterization and Application in Biology and Medicine  10.1016/B978-0-08-102015-9.00018-6
Azevedo HS and Da Silva RMP (2018). Self-assembling biomaterials: Molecular design, characterization and application in biology and medicine. 10.1016/C2016-0-00524-7
Banerjee J, Radvar E and Azevedo HS (2018). 10 Self-assembling peptides and their application in tissue engineering and regenerative medicine. Peptides and Proteins as Biomaterials For Tissue Regeneration and Repair  10.1016/b978-0-08-100803-4.00010-3
Shuturminska K, O'Malley C, Collis DWP, Conde J and Azevedo HS (2018). 17 Displaying biofunctionality on materials through templated self-assembly. Self-Assembling Biomaterials  10.1016/b978-0-08-102015-9.00018-6

2017

Hartweg M, Edwards-Gayle CJC, Radvar E, Collis D, Reza M, Kaupp M, Steinkoenig J, Ruokolainen J, Rambo R, Barner-Kowollik C, Hamley IW, Azevedo HS and Becer CR (2017). Ugi multicomponent reaction to prepare peptide-peptoid hybrid structures with diverse chemical functionalities. Polymer Chemistry  vol. 9, (4) 482-489. 10.1039/c7py01953j
Banerjee J and Azevedo HS (2017). Crafting of functional biomaterials by directed molecular self-assembly of triple helical peptide building blocks. Interface Focus  vol. 7, (6) 20160138-20160138. 10.1098/rsfs.2016.0138
Ribeiro S, Radvar E, Shi Y, Borges J, Pirraco RP, Leonor IB, Mano JF, Reis RL, Mata Á and Azevedo HS (2017). Nanostructured interfacial self-assembled peptide–polymer membranes for enhanced mineralization and cell adhesion. Royal Society of Chemistry (Rsc)  Nanoscale  vol. 9, (36) 13670-13682. 10.1039/c7nr03410e
Shuturminska K, Tarakina NV, Azevedo HS, Bushby AJ, Mata A, Anderson P and Al-Jawad M (2017). Elastin-Like Protein, with Statherin Derived Peptide, Controls Fluorapatite Formation and Morphology. Front Physiol  vol. 8, 368-368. 10.3389/fphys.2017.00368
Shi Y, Hu Y, Ochbaum G, Lin R, Bitton R, Cui H and Azevedo HS (2017). Enzymatic activation of cell-penetrating peptides in self-assembled nanostructures triggers fibre-to-micelle morphological transition. Royal Society of Chemistry (Rsc)  Chemical Communications  vol. 53, (52) 7037-7040. 10.1039/c7cc03512h
MATA A, Azevedo HS, Botto L, Gavara N and Su L (2017). New Bioengineering Breakthroughs and Enabling Tools in Regenerative Medicine. Current Stem Cell Reports  10.1007/s40778-017-0081-9
Shi Y, Conde J and Azevedo HS (2017). Empowering the potential of cell-penetrating peptides for targeted intracellular delivery via molecular self-assembly. 10.1007/978-3-319-66095-0_12

2016

Martins IM, Reis RL and Azevedo HS (2016). Phage Display Technology in Biomaterials Engineering: Progress and Opportunities for Applications in Regenerative Medicine. Acs Chem Biol  10.1021/acschembio.5b00717
Banerjee J, Shi Y and Azevedo HS (2016). In vitro blood-brain barrier models for drug research: state-of-the-art and new perspectives on reconstituting these models on artificial basement membrane platforms. Elsevier  Drug Discovery Today  vol. early view online, 1367-1386. 10.1016/j.drudis.2016.05.020

2015

Balmayor ER, Baran TE, Unger M, Marques AP, Azevedo HS and Reis RL (2015). Presence of starch enhances in vitro biodegradation and biocompatibility of a gentamicin delivery formulation. Journal of Biomedical Materials Research - Part B Applied Biomaterials  vol. 103, (8) 1610-1620. 10.1002/jbm.b.33343
Azevedo HS and Pashkuleva I (2015). Biomimetic supramolecular designs for the controlled release of growth factors in bone regeneration. Advanced Drug Delivery Reviews  vol. 94, 63-76. 10.1016/j.addr.2015.08.003
Inostroza-Brito KE, Collin E, Siton-Mendelson O, Smith KH, Monge-Marcet A, Ferreira DS, Rodríguez RP, Alonso M, Rodríguez-Cabello JC, Reis RL, Sagués F, Botto L, Bitton R, Azevedo HS and Mata A (2015). Co-Assembly, spatiotemporal control and morphogenesis of a hybrid protein-peptide system. Nature Chemistry  vol. 7, (11) 897-904. 10.1038/nchem.2349
Pereira RC, Costa-Pinto AR, Frias AM, Neves NM, Azevedo HS and Reis RL (2015). In vitro chondrogenic commitment of human Wharton's jelly stem cells by co-culture with human articular chondrocytes. Wiley  Journal of Tissue Engineering and Regenerative Medicine  vol. 11, (6) 1876-1887. 10.1002/term.2085
Conde J, Bao C, Tan Y, Cui D, Edelman ER, Azevedo HS, Byrne HJ, Artzi N and Tian F (2015). Tumor Targeting: Dual Targeted Immunotherapy via In Vivo Delivery of Biohybrid RNAi‐Peptide Nanoparticles to Tumor‐Associated Macrophages and Cancer Cells (Adv. Funct. Mater. 27/2015). Advanced Functional Materials  vol. 25, (27) 4173-4173. 10.1002/adfm.201570181
Conde J, Bao C, Tan Y, Cui D, Edelman ER, Azevedo HS, Byrne HJ, Artzi N and Tian F (2015). Dual Targeted Immunotherapy via in Vivo Delivery of Biohybrid RNAi-Peptide Nanoparticles to Tumor-Associated Macrophages and Cancer Cells. Advanced Functional Materials  vol. 25, (27) 4183-4194. 10.1002/adfm.201501283
Ferreira DS, Lin Y-A, Cui H, Hubbell JA, Reis RL and Azevedo HS (2015). Molecularly engineered self-assembling membranes for cell-mediated degradation. Adv Healthc Mater  vol. 4, (4) 602-612. 10.1002/adhm.201400586

2014

Susano MA, Leonor IB, Reis RL and Azevedo HS (2014). Elastic biodegradable starch/ethylene-co-vinyl alcohol fibre-mesh scaffolds for tissue engineering applications. Journal of Applied Polymer Science  vol. 131, (14) 10.1002/app.40504

2013

Mendes AC, Baran ET, Reis RL and Azevedo HS (2013). Self-assembly in nature: using the principles of nature to create complex nanobiomaterials. Wiley Interdiscip Rev Nanomed Nanobiotechnol  vol. 5, (6) 582-612. 10.1002/wnan.1238
Mendes AC, Baran ET, Reis RL and Azevedo HS (2013). Self-assembly in nature: Using the principles of nature to create complex nanobiomaterials. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology  vol. 5, (6) 582-612. 10.1002/wnan.1238
Ferreira DS, Reis RL and Azevedo HS (2013). Peptide-based microcapsules obtained by self-assembly and microfluidics as controlled environments for cell culture. Soft Matter  vol. 9, (38) 9237-9248. 10.1039/c3sm51189h
Ferreira DS, Marques AP, Reis RL and Azevedo HS (2013). Hyaluronan and self-assembling peptides as building blocks to reconstruct the extracellular environment in skin tissue. Biomaterials Science  vol. 1, (9) 952-964. 10.1039/c3bm60019j
Mendes AC, Smith KH, Tejeda-Montes E, Engel E, Reis RL, Azevedo HS and Mata A (2013). Co-assembled and microfabricated bioactive membranes. Advanced Functional Materials  vol. 23, (4) 430-438. 10.1002/adfm.201201065
Mendes AC, Smith KH, Tejeda‐Montes E, Engel E, Reis RL, Azevedo HS and Mata A (2013). Bioactive Membranes: Co‐Assembled and Microfabricated Bioactive Membranes (Adv. Funct. Mater. 4/2013). Advanced Functional Materials  vol. 23, (4) 397-397. 10.1002/adfm.201370017
Mendes AC, Baran ET, Reis RL and Azevedo HS (2013). Fabrication of phospholipid-xanthan microcapsules by combining microfluidics with self-assembly. Acta Biomaterialia  10.1016/j.actbio.2013.01.035
Gomes M, Azevedo H, Malafaya P, Silva S, Oliveira J, Silva G, João Mano RS and Reis R (2013). Natural Polymers in Tissue Engineering Applications. Handbook of Biopolymers and Biodegradable Plastics: Properties, Processing and Applications  10.1016/B978-1-4557-2834-3.00016-1
Gomes M, Azevedo H, Malafaya P, Silva S, Oliveira J, Silva G, Mano RSJ and Reis R (2013). 16 Natural Polymers in Tissue Engineering Applications. Handbook of Biopolymers and Biodegradable Plastics  10.1016/b978-1-4557-2834-3.00016-1

2012

Alves NM, Leonor IB, Azevedo HS, Reis RL and Mano JF (2012). Surfaces Inducing Biomineralization. 10.1002/9783527652273.ch15
Mendes AC, Baran ET, Lisboa P, Reis RL and Azevedo HS (2012). Microfluidic fabrication of self-assembled peptide-polysaccharide microcapsules as 3D environments for cell culture. Biomacromolecules  vol. 13, (12) 4039-4048. 10.1021/bm301332z
Smith KH, Inostroza KE, Alonso M, Reis RL, Azevedo HS and Mata A (2012). Spontaneous co-assembly of molecularly designed building blocks into hierarchically ordered, dynamic, hybrid macrotubes. Journal of Tissue Engineering and Regenerative Medicine  vol. 6, 224-225.
Mendes AC, Baran ET, Pereira RC, Azevedo HS and Reis RL (2012). Encapsulation and Survival of a Chondrocyte Cell Line within Xanthan Gum Derivative. Macromolecular Bioscience  vol. 12, (3) 350-359. 10.1002/mabi.201100304
Balmayor ER, Baran ET, Azevedo HS and Reis RL (2012). Injectable biodegradable starch/chitosan delivery system for the sustained release of gentamicin to treat bone infections. Carbohydrate Polymers  vol. 87, (1) 32-39. 10.1016/j.carbpol.2011.06.078

2011

Susano M, Frias AM, Leonor IB, Reis RL and Azevedo HS (2011). Biodegradable fiber-mesh scaffolds with elastic properties and their potential use in tissue engineering. 24th European Conference On Biomaterials - Annual Conference of The European Society For Biomaterials 
Mendes AC, Baran ET, Nunes C, Coimbra MA, Azevedo HS and Reis RL (2011). Palmitoylation of xanthan polysaccharide for self-assembly microcapsule formation and encapsulation of cells in physiological conditions. Soft Matter  vol. 7, (20) 9647-9658. 10.1039/c1sm05594a
Mendes AC, Baran ET, Azevedo HS and Reis RL (2011). MICROFLUIDIC ENCAPSULATION OF CELLS INTO SELF-ASSEMBLING XANTHAN-PHOSPOLIPID AMPHIPHILE FOR CELL THERAPY. International Journal of Artificial Organs  vol. 34, (8) 623-623.
Pereira RC, Scaranari M, Gentili C, Cancedda R, Frias AM, Reis RL and Azevedo HS (2011). HYALURONIC ACID MICROPARTICLES AS INJECTABLE DRUG CARRIER FOR KNEE CARTILAGE REPAIR: EFFECT ON ARTICULAR CHONDROCYTE BEHAVIOR. International Journal of Artificial Organs  vol. 34, (8) 667-667.
Balmayor ER, Pashkuleva I, Frias AM, Azevedo HS and Reis RL (2011). Synthesis and functionalization of superparamagnetic poly-ε- caprolactone microparticles for the selective isolation of subpopulations of human adipose-derived stem cells. Journal of The Royal Society Interface  vol. 8, (59) 896-905. 10.1098/rsif.2010.0531
Balmayor ER, Azevedo HS and Reis RL (2011). Controlled delivery systems: From pharmaceuticals to cells and genes. Pharmaceutical Research  vol. 28, (6) 1241-1258. 10.1007/s11095-011-0392-y
Pereira RC, Gentili C, Cancedda R, Azevedo HS and Reis RL (2011). Encapsulation of human articular chondrocytes into 3D hydrogel: phenotype and genotype characterization. Methods in Molecular Biology (Clifton, N.J.)  vol. 695, 167-181. 10.1007/978-1-60761-984-0_11

2010

Pashkuleva I, López-Pérez PM, Azevedo HS and Reis RL (2010). Highly porous and interconnected starch-based scaffolds: Production, characterization and surface modification. Materials Science and Engineering C  vol. 30, (7) 981-989. 10.1016/j.msec.2010.04.019
Alves NM, Leonor IB, Azevedo HS, Reis RL and Mano JF (2010). Designing biomaterials based on biomineralization of bone. Journal of Materials Chemistry  vol. 20, (15) 2911-2921. 10.1039/b910960a
Bessa PC, Balmayor ER, Azevedo HS, Nürnberger S, Casal M, Van Griensven M, Reis RL and Redl H (2010). Silk fibroin microparticles as carriers for delivery of human recombinant BMPs. Physical characterization and drug release. Journal of Tissue Engineering and Regenerative Medicine  vol. 4, (5) 349-355. 10.1002/term.245

2009

Leonor IB, Alves CM, Azevedo HS and Reis RL (2009). Effects of protein incorporation on calcium phosphate coating. Materials Science and Engineering C  vol. 29, (3) 913-918. 10.1016/j.msec.2008.08.003
Balmayor ER, Feichtinger GA, Azevedo HS, Van Griensven M and Reis RL (2009). Starch-poly-ε-caprolactone microparticles reduce the needed amount of BMP-2. Clinical Orthopaedics and Related Research  vol. 467, (12) 3138-3148. 10.1007/s11999-009-0954-z
Martins AM, Pereira RC, Leonor IB, Azevedo HS and Reis RL (2009). Chitosan scaffolds incorporating lysozyme into CaP coatings produced by a biomimetic route: A novel concept for tissue engineering combining a self-regulated degradation system with in situ pore formation. Acta Biomaterialia  vol. 5, (9) 3328-3336. 10.1016/j.actbio.2009.05.027
Azevedo HS and Reis RL (2009). Encapsulation of α-amylase into starch-based biomaterials: An enzymatic approach to tailor their degradation rate. Acta Biomaterialia  vol. 5, (8) 3021-3030. 10.1016/j.actbio.2009.04.039
Balmayor ER, Tuzlakoglu K, Azevedo HS and Reis RL (2009). Preparation and characterization of starch-poly-ε-caprolactone microparticles incorporating bioactive agents for drug delivery and tissue engineering applications. Acta Biomaterialia  vol. 5, (4) 1035-1045. 10.1016/j.actbio.2008.11.006
Pereira RC, Scaranari M, Castagnola P, Grandizio M, Azevedo HS, Reis RL, Cancedda R and Gentili C (2009). Novel injectable gel (system) as a vehicle for human articular chondrocytes in cartilage tissue regeneration. Journal of Tissue Engineering and Regenerative Medicine  vol. 3, (2) 97-106. 10.1002/term.145

2008

Capito RM, Azevedo HS, Velichko Y, Mata A and Stupp SI (2008). Self-assembly of biomaterials at an interface: Formation of sacs, membranes, and strings. 8th World Biomaterials Congress 2008  vol. 1,
Balmayor ER, Baran ET, Azevedo HS and Reis RL (2008). Highly biodegradable starch-conjugated chitosan microspheres as carriers for the controlled release of aminoglycosides antibiotic drugs. 8th World Biomaterials Congress 2008  vol. 1,
Pereira R, Scaranari M, Castagnola P, Grandizio M, Azevedo H, Reis RL, Cancedda R and Gentili C (2008). Novel injectable gel system as a vehicle for human articular chondrocytes encapsulation for cartilage tissue regeneration. 8th World Biomaterials Congress 2008  vol. 3,
Gomes M, Azevedo H, Malafaya P, Silva S, Oliveira J, Silva G, Sousa R, Mano J and Reis R (2008). Natural Polymers in Tissue Engineering Applications. 10.1016/B978-0-12-370869-4.00006-9
Martins AM, Santos MI, Azevedo HS, Malafaya PB and Reis RL (2008). Natural origin scaffolds with in situ pore forming capability for bone tissue engineering applications. Acta Biomater  vol. 4, (6) 1637-1645. 10.1016/j.actbio.2008.06.004
Balmayor ER, Tuzlakoglu K, Marques AP, Azevedo HS and Reis RL (2008). A novel enzymatically-mediated drug delivery carrier for bone tissue engineering applications: Combining biodegradable starch-based microparticles and differentiation agents. Journal of Materials Science: Materials in Medicine  vol. 19, (4) 1617-1623. 10.1007/s10856-008-3378-5
Capito RM, Azevedo HS, Velichko YS, Mata A and Stupp SI (2008). Self-assembly of large and small molecules into hierarchically ordered sacs and membranes. Science  vol. 319, (5871) 1812-1816. 10.1126/science.1154586
Pashkuleva I, Azevedo HS and Reis RL (2008). Surface structural investigation of starch-based biomaterials. Macromolecular Bioscience  vol. 8, (2) 210-219. 10.1002/mabi.200700076
Gomes ME, Azevedo HS, Moreira AR, Ellä V, Kellomäki M and Reis RL (2008). Starch-poly(ε-caprolactone) and starch-poly(lactic acid) fibre-mesh scaffolds for bone tissue engineering applications: Structure, mechanical properties and degradation behaviour. Journal of Tissue Engineering and Regenerative Medicine  vol. 2, (5) 243-252. 10.1002/term.89
Reis RL, Neves NM, Mano JF, Gomes ME, Marques AP and Azevedo HS (2008). Natural-based polymers for biomedical applications. Natural-Based Polymers For Biomedical Applications  1-802. 10.1533/9781845694814
Azevedo HS, Santos TC and Reis RL (2008). Controlling the degradation of natural polymers for biomedical applications. 10.1533/9781845694814.1.106
Reis RL, Neves NM, Mano JF, Gomes ME, Marques AP and Azevedo HS (2008). Preface. Natural-Based Polymers For Biomedical Applications  10.1016/B978-1-84569-264-3.50034-2
Gomes M, Azevedo H, Malafaya P, Silva S, Oliveira J, Silva G, Sousa R, Mano J and Reis R (2008). Chapter 6 Natural Polymers in tissue engineering applications. Tissue Engineering  10.1016/b978-0-12-370869-4.00006-9
Azevedo HS, Santos TC and Reis RL (2008). 4 Controlling the degradation of natural polymers for biomedical applications. Natural-Based Polymers For Biomedical Applications  10.1533/9781845694814.1.106

2007

Mano JF, Silva GA, Azevedo HS, Malafaya PB, Sousa RA, Silva SS, Boesel LF, Oliveira JM, Santos TC, Marques AP, Neves NM and Reis RL (2007). Natural origin biodegradable systems in tissue engineering and regenerative medicine: Present status and some moving trends. Journal of The Royal Society Interface  vol. 4, (17) 999-1030. 10.1098/rsif.2007.0220

2006

Boesel LF, Azevedo HS and Reis RL (2006). Incorporation of α-amylase enzyme and a bioactive filler into hydrophilic, partially degradable, and bioactive cements (HDBCs) as a new approach to tailor simultaneously their degradation and bioactive behavior. Biomacromolecules  vol. 7, (9) 2600-2609. 10.1021/bm060387j
Azevedo HS, Leonor IB and Reis RL (2006). Incorporation of proteins with different isoelectric points into biomimetic Ca-P coatings: A new approach to produce hybrid coatings with tailored properties. Key Engineering Materials  vol. 309-311 II, 755-758. 10.4028/0-87849-992-x.755

2005

Azevedo HS, Leonor IB, Alves CM and Reis RL (2005). Incorporation of proteins and enzymes at different stages of the preparation of calcium phosphate coatings on a degradable substrate by a biomimetic methodology. Materials Science and Engineering C  vol. 25, (2) 169-179. 10.1016/j.msec.2005.01.007

2004

Azevedo HS, Leonor IB, Alves CM, Goldsmith RJ and Reis RL (2004). Influence of protein incorporation in the nucleation and growth of biomimetic calcium phosphate coatings. Transactions - 7th World Biomaterials Congress 
Martins AM, Malafaya PB, Azevedo HS, Santos MI, Coutinho OP and Reis RL (2004). Natural origin scaffolds with in situ gradual pore forming capability: Development and characterization. Transactions - 7th World Biomaterials Congress 
Azevedo HS and Reis RL (2004). Effect of incubation conditions and enzyme cocktails on the in vitro degradation behaviour of different starch-based biomaterials. Transactions - 7th World Biomaterials Congress 
Boesel LF, Azevedo HS and Reis RL (2004). Novel hydrophilic, partially degradable and bioactive bone cements containing starch and a bioactive glass. Transactions - 7th World Biomaterials Congress 

2003

Azevedo HS, Gama FM and Reis RL (2003). In vitro assessment of the enzymatic degradation of several starch based biomaterials. Biomacromolecules  vol. 4, (6) 1703-1712. 10.1021/bm0300397
Oliveira AL, Leonor IB, Malafaya PB, Alves CM, Azevedo HS and Reis RL (2003). Tailoring the bioactivity of natural origin inorganic - Polymeric based systems. Key Engineering Materials  vol. 240-242, 111-142. 10.4028/www.scientific.net/kem.240-242.111
Leonor IB, Azevedo HS, Alves CM and Reis RL (2003). Effects of the incorporation of proteins and active enzymes on biomimetic calcium-phosphate coatings. Key Engineering Materials  vol. 240-242, 97-100. 10.4028/www.scientific.net/kem.240-242.97

2002

Azevedo H, Bishop D and Cavaco-Paulo A (2002). Possibilities for recycling cellulases after use in cotton processing: Part I: Effects of end-product inhibition, thermal and mechanical deactivation, and cellulase depletion by adsorption. Applied Biochemistry and Biotechnology - Part a Enzyme Engineering and Biotechnology  vol. 101, (1) 61-75. 10.1385/ABAB:101:1:61
Azevedo H, Bishop D and Cavaco-Paulo A (2002). Possibilities for recycling cellulases after use in cotton processing: Part II: Separation of cellulases from reaction products and released dyestuffs by ultrafiltration. Applied Biochemistry and Biotechnology - Part a Enzyme Engineering and Biotechnology  vol. 101, (1) 77-91. 10.1385/ABAB:101:1:77

2001

Azevedo H, Pereira Ramos L and Cavaco-Paulo A (2001). Desorption of cellulases from cotton powder. Biotechnology Letters  vol. 23, (17) 1445-1448. 10.1023/A:1011619425613
Azevedo H and Cavaco-Paulo A (2001). Recovery of cellulases after textile processing. Abstracts of Papers of The American Chemical Society  vol. 221, U176-U176.

2000

Azevedo H, Bishop D and Cavaco-Paulo A (2000). Effects of agitation level on the adsorption, desorption, and activities on cotton fabrics of full length and core domains of EGV (Humicola insolens) and CenA (Cellulomonas fimi). Enzyme and Microbial Technology  vol. 27, (3-5) 325-329. 10.1016/S0141-0229(00)00205-2

1999

Andreaus J, Azevedo H and Cavaco-Paulo A (1999). Effects of temperature on the cellulose binding ability of cellulase enzymes. Journal of Molecular Catalysis - B Enzymatic  vol. 7, (1-4) 233-239. 10.1016/S1381-1177(99)00032-6

Grants

Grants of specific relevance to
Light4Sight - Light-activated carriers for the controlled delivery of therapeutic peptides in posterior segment eye diseases
Azevedo H and Lyu Y
£179,947 European Commission (01-11-2019 - 31-10-2021)